Opinion|Videos|April 4, 2025

Evaluating the Safety of Topical JAK Inhibitors in the Pediatric Population: Insights into Systemic Risks and Adverse Effects

Aaron Farberg, MD, discuss how JAK inhibitors have come under scrutiny in the past for systemic adverse effects in oral formulations, while exploring the safety data of topical JAK inhibitors in the pediatric population, which appears to show a more favorable risk profile with localized effects.

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This news content has been independently developed and is not endorsed by the American Academy of Dermatology.

Video content above is prompted by the following:

  • JAK inhibitors have come under scrutiny in the past for systemic adverse effects in oral formulations. How do you interpret the safety data of topical JAK inhibitors in the pediatric population?

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