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Wayne Kuznar
Articles
Fine tuning dosing schedules of targeted agents may improve responses in melanoma
April 19, 2018
Changing the schedule of targeted therapies has been shown to improve the response rate in a mouse model of melanoma.
Immunity persists for at least 3 years after receipt of new shingles vaccine
April 18, 2018
Immune responses to the latest shingles vaccine (Shingrix) last for at least three years following vaccination. The robust immune responses develop and persist in all age groups, according to a recent study in The Journal of Infectious Diseases.
Filaggrin degradation products may explain higher rate of dermatitis in the winter
April 16, 2018
A decrease in the levels of natural moisturizing factors and an increase in the density of corneocytes may explain why dermatitis and xerosis are worse in the winter.
Dupilumab controls atopic dermatitis symptoms in patients with asthma
March 19, 2018
Adults with moderate to severe atopic dermatitis with comorbid asthma experience the same improvement in disease signs and symptoms with dupilumab treatment as those without asthma, according to pooled data from two large phase three clinical trials.
The atopic march strides toward eosinophilic esophagitis
March 19, 2018
Eczema, food allergy, and asthma independently and cumulatively increase the risk for eosinophilic esophagitis (EoE), according to findings presented at the 2018 American Academy of Allergy, Asthma & Immunology and World Allergy Organization Joint Congress in Orlando.
Common Staph strain on skin protects against skin neoplasia
March 19, 2018
A strain of Staphylococcus epidermidis, a common microbe on healthy human skin, produces a chemical compound that has the ability to impair growth of skin neoplasia, researchers have found.
Shift to short chain fatty acids in the skin may explain AD lesions
March 19, 2018
Alterations in lipid metabolism can be detrimental to skin barrier function leading to atopic dermatitis, researchers have found.
Gene identified as having a role in suppressing atopic dermatitis
March 12, 2018
The transcription factor "retinoid-related orphan receptor-alpha" (RORA) has been identified as a regulator of T regulatory (Treg) genes responsible for suppressing allergic skin inflammation, researchers report.