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and joined the MJH Life Sciences team in February 2023. She attended Kent State University and earned a Bachelor of Science degree in journalism with minors in public relations and creative writing. She enjoys making and listening to music, reading, and spending time with her cats, Astrid and Marceline.

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Catch up on dermatology news, highlights, and insights from the past 24 hours.

Daily Derm Times: March 24, 2025

Maddi Hebebrand is an associate editor of 

and joined the MJH Life Sciences team in May 2024. She attended Baldwin Wallace University, studying Media Production and Film, and is now finishing her Masters in Digital Media through Ohio University. When she's not writing, Maddi loves to read, attend concerts and spend time with her family.

The study identified 2 fungal profiles in AD patients, with 1 subgroup exhibiting distinct fungal dysbiosis.

The Mycobiome Connection: How Fungi Influence AD

Kaitlyn Bader is the assistant managing editor of 

 and joined the MJH Life Sciences team in June 2022. She attended Otterbein University in Westerville, Ohio, and earned a Bachelor of Arts degree in literary studies with minors in creative writing and film studies. Prior to health care news, Kaitlyn worked in industrial marketing. She enjoys cooking, reading, and tending to her house plants.

Asha Patel Shah, MD, MBA, FAAD, discusses recent research on retinol and retinoid bioactivity when layered with moisturizers highlighted at AAD 2025.

“Open Sandwich” Moisturization Regimen Does Not Affect Bioactivity of Retinols and Retinoids 

Marie Bosslett is the assistant editor of 

 and joined the MJH Life Sciences team in October 2024. She attended Loyola University Maryland in Baltimore and earned a Bachelor of Arts in Communication with minors in marketing and writing. When she’s not writing, Marie enjoys going to concerts, reading on the beach, and spending time with friends and family.

Participants from the parent DELTA 1 and 2 studies maintained their disease control and observed a decrease in pain and itch over 52 weeks of treatment.

DELTA 3 Showcases Long-Term Safety and Efficacy of Delgocitinib for Chronic Hand Eczema

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Sydney Givens, PA-C, reviews how she discusses cosmeceuticals with her patients and what resources she offers. 

Patients Want Cosmeceutical Recommendations, What Do You Need to Know?  

Givens presented tips for all dermatology providers to consider at the 2023 Fall Clinical Dermatology Conference for PAs and NPs.  

Sydney Givens, PA-C, Reviews How to Discuss Cosmeceuticals With Patients  

Final Thoughts: The Importance of Comparative Studies in AD

Panelists offer concluding insights and emphasize the critical role of comparative studies in advancing atopic dermatitis treatment strategies.

clinical

Video Series

' Sunday Crossword, where dermatology knowledge meets fun! Each week, we curate a selection of words and terms pulled directly from the latest news in the dermatology world. Whether it's breakthrough treatments, new research findings, or emerging trends, this crossword serves as both a challenge and an opportunity to reinforce your expertise in the field.

For more in-depth insights, don't forget to check out our 

, where we break down the most important stories and updates from the past week. And to stay ahead of the curve and prepare for future crosswords, make sure to follow our content throughout the week.

Try out either our interactive crossword or a static/non-interactive version below.

 Type of skin cancer linked to increased suicide risk in a recent review.

 Agents used to break down excess keratin in conditions like psoriasis.

 Chronic inflammatory skin condition (abbreviated) discussed in a Frontline Forum supplement.

 Investigational therapy for chronic spontaneous urticaria.

 Type of laser found to be effective for acquired dermal melanocytosis.

 Skin disease treated with ixekizumab in a long-term Japanese study.

 AI-designed drug analyzed for efficacy across patient groups.

 Hormone therapy linked to increased skin cancer risk.

 Biologic therapy for AD associated with pediatric ocular adverse effects.

 Abbreviation for a condition improved by mitochondrial complex I-blocking drugs.

For answers to this week's puzzle, check out next week's edition of the 

Answers from our March 16, 2025 puzzle: [Across: 3- Effaclar; 5 - Cosentyx; 6 - Bunick; 7 - Bimzelx; 9 - NEA; Down: 1 - DMNA; 2 - microneedling; 3 - EltaMD; 4 - zonulin; 8 - Mohs]

Dermatology Times' Sunday Crossword combines dermatology knowledge with entertainment, featuring terms from recent dermatology news. It covers breakthrough treatments, research findings, and trends, offering a fun way to reinforce expertise. The crossword is available in both interactive and static formats. Clues include topics like skin cancer, psoriasis treatments, and investigational therapies. Dermatology professionals can enhance their knowledge by engaging with the crossword and staying updated through the Weekly Roundup, which provides detailed insights into the most significant stories and updates in dermatology.

Test your knowledge of key words and terms associated with dermatology news from the previous week.

Quizzes

Dermatology Times' Sunday Crossword: March 23, 2025

Welcome to this week’s roundup of the most insightful and impactful articles from the sister publications of 

. Our network brings together expert perspectives, clinical advancements, and industry updates to keep clinicians informed and ahead of the curve. From cutting-edge treatments to practice management strategies, here’s a look at the top stories shaping the field of medicine.

Study highlights how PCOS alters uterine lining

revealed significant differences in uterine lining composition between women with polycystic ovary syndrome (PCOS) and those without the condition. Researchers developed a detailed cell map of endometrial tissue, identifying disrupted gene expression in PCOS patients, which may contribute to fertility challenges, miscarriage risk, and increased susceptibility to endometrial cancer. The study analyzed tissue samples from 12 women with PCOS and 5 healthy controls, assessing hormone levels, ovarian function, and endometrial cell types. Findings showed an increased proportion of epithelial cells and fewer stromal and lymphoid cells in PCOS patients, with little change after intervention. Metformin treatment helped regulate some hormonal imbalances and partially restored estrogen-α expression in certain epithelial subpopulations.

Unmasking Long COVID: Dr Noah Greenspan on Recovery, Research Gaps, and the Future of Treatment

, Noah Greenspan, DPT, PT, CCS, EMT-B, discusses the challenges of Long COVID (LC) and the ongoing need for research and recognition. A specialist in cardiopulmonary rehabilitation, Greenspan highlights LC’s overlap with post-viral syndromes like ME/CFS and the lack of standardized diagnostic criteria. He emphasizes careful activity management, hydration, compression garments, and oxygen therapy as key strategies for symptom relief. While research has improved awareness, major gaps remain in funding and acceptance. Greenspan stresses the importance of patient advocacy and continued medical focus to address LC’s long-term impact.

Advocates for those with Down syndrome dread prospect of Medicaid cuts

, Heather Sachs of the National Down Syndrome Congress warns of the potential impact of Medicaid cuts on individuals with Down syndrome. With Congress considering major reductions in Medicaid funding, Sachs calls it a “5-alarm fire,” stressing that cuts could limit access to essential healthcare, home and community-based services, and school programs. She also raises concerns about proposed Medicaid work requirements, which could lead to millions losing coverage. Sachs urges continued advocacy, emphasizing that past efforts have successfully protected health care access. “We have to keep fighting,” she says.

Q&A: Knowledge is Key for Adapting AI within Pharmacy Practice

, Don Roosan, PharmD, PhD, emphasizes the transformative potential of AI in pharmacy. He believes AI, including large-language models like ChatGPT, will revolutionize the field, making processes more efficient and empowering pharmacists to make informed decisions. While concerns exist, Roosan stresses that “knowledge is power” and encourages pharmacists to understand AI’s capabilities and biases. He highlights the importance of education in overcoming fear, noting that AI will create new opportunities rather than just replace jobs. “This is just the beginning,” Roosan says, urging pharmacists to embrace AI for better patient care.

The First Optimized Self-Replicating RNA (srRNA) Technology

 inaugural Pivotal Paper series, experts discuss groundbreaking advances in self-replicating RNA (srRNA) vaccine technology. The featured study, published in Springer Nature, highlights srRNA’s superior bioactivity, dose-sparing potential, and durable immune response compared to traditional mRNA vaccines. Panelists, including industry leaders Philip Dormitzer, PhD, and Andy Geall, PhD, emphasize the technology's scalability and potential for single-dose vaccines. The study demonstrated the safety and immunogenicity of an optimized srRNA rabies vaccine in humans, opening pathways for broader applications in infectious diseases, cancer vaccines, and protein replacement therapies.

Want to read more on specialty care, pharmacy, industry sciences, and more? Check out 

MJH Life Sciences full list of brands here.

Recent research has identified significant differences in uterine lining composition in women with PCOS, potentially affecting fertility and cancer risk. Long COVID remains a challenge, with ongoing research gaps and the need for patient advocacy. Medicaid cuts could severely impact individuals with Down syndrome, limiting access to essential services. AI is poised to transform pharmacy practice, with education crucial for overcoming biases and fears. Advances in self-replicating RNA technology promise enhanced vaccine efficacy and scalability, with potential applications in infectious diseases and cancer.

This week, we feature top articles from our sister publications on long COVID recovery, integrating AI into pharmacy, and more.

The Rx Recap: March 16-22

To stay up-to-date with the latest dermatology news, sign up to receive our 

BREAKING NEWS: Benzene Found in Various Acne Products; Valisure Files Petition With FDA to Recall Treatments

igh levels of the cancer-causing chemical benzene were found in various benzoyl peroxide (BPO) acne products

 from major brands, including Proactiv, Clinique, Clearasil, and more.

, an independent testing laboratory, filed a petition with the 

, requesting a recall of treatments affected by elevated levels of the carcinogen in order to allow regulators to investigate.

The COVID-19 pandemic significantly affected patients with immune-mediated inflammatory diseases (DIMIDs), including atopic dermatitis (AD), psoriasis, and vitiligo. The fear of morbidity, mortality, and vaccine hesitancy contributed to disruptions in their daily lives. Patients with immunodeficiency diseases, older individuals, males, and those of non-White ethnicity were at an increased risk of severe COVID-19 outcomes. Interestingly, vaccination, a healthy diet, and atopic conditions were considered protective factors against COVID-19. A recent prospective observational, multicenter, multidisciplinary cohort substudy explored the impact of COVID-19 disease and vaccination on DIMIDs, specifically AD, psoriasis, and vitiligo.

L'Oréal Issues Voluntary Recall of Benzoyl Peroxide Products Over Benzene Concerns

L’Oréal announced it is recalling all lots of its acne treatment

 in the US due to concerns over benzene contamination. The product, sold under the 

 brand, contains benzoyl peroxide (BPO).

first reported benzene contamination in several BPO-containing acne products

 more than a year ago, urging the US Food and Drug Administration (FDA) to take action.

Amlitelimab Demonstrates Durable Response in Atopic Dermatitis

2025 American Academy of Dermatology (AAD) Annual Meeting

shared new insights into the effectiveness of amlitelimab

, an investigational drug for atopic dermatitis (AD).

Data from the phase 2b STREAM-AD and RIVER-AD studies demonstrated promising findings for patients with moderate to severe AD, with results showcasing durable efficacy and a favorable safety profile.

Karl Yen, executive global project head for amlitelimab at Sanofi, spoke with Dermatology Times to share key insights from these studies, highlighting the potential of amlitelimab as a transformative treatment option for AD.

A Walk Through The AAD 2025 Poster Hall: The Must-See Research Shaping Dermatology

 showcased a wealth of innovative research and findings from across the specialty.

In this roundup, we’ve compiled the key takeaways from the posters and abstracts presented, offering you an inside look at the latest trends and developments. Explore full 

Recent findings have revealed benzene contamination in various benzoyl peroxide acne products, prompting Valisure to petition the FDA for recalls. The COVID-19 pandemic has notably impacted patients with immune-mediated inflammatory diseases, with certain demographics at higher risk for severe outcomes. L'Oréal has voluntarily recalled its Effaclar Duo product due to benzene concerns. Amlitelimab has shown durable efficacy in treating atopic dermatitis, as presented at the 2025 AAD Annual Meeting. The meeting also highlighted significant dermatological research advancements through its poster hall presentations.

Explore the top headlines of the week including insights on voluntary recalls, DIMIDs and pandemic risks, and AAD pearls.

Top 5 Articles of the Week: March 16-21

Unraveling the Molecular Mechanism of Clindamycin Binding in Cutibacterium acnes and Resistance Development: Insights From Cryo-EM

Cryo-EM reveals molecular mechanisms of clindamycin resistance in Cutibacterium acnes, highlighting key mutations affecting antibiotic binding.

Povorcitinib Demonstrates Promising Phase 3 Results for Hidradenitis Suppurativa Treatment

Incyte’s phase 3 STOP-HS trials demonstrated significant efficacy and safety of povorcitinib in moderate to severe hidradenitis suppurativa.

Social Media “Hacks”: DIY Sunscreen, Slugging, and More With Chris Tomassian, MD

Tomassian noted unrealistic beauty standards fueled by social media filters and edited images have led to distorted expectations.

Climate Change, Pollution’s Growing Impact on Dermatology

Experts stressed the importance of dermatologists engaging in climate advocacy and adopting sustainable practices, as their actions may inspire others to follow suit.

Medical Device Ialuxid Gel Is Successful in Treating Mild to Moderate Acne

Patients observed a 56% reduction in lesions after 56 days of treatment with only mild adverse events.

Essential AAD Late Breakers That Could Change Your Practice

Explore a comprehensive roundup of the most important AAD late breakers, all in one place – key insights from the latest dermatology research.

Bridging the Gender Gap: Women Leading the Way

 in celebrating the women who make this field shine through their patient interactions, clinical insights, and research.

Discover the latest research from the AAD poster hall, compiled in one place for dermatology professionals.

Analyzing Current Procedures for Periorbital Hyperpigmentation

A comprehensive evaluation of therapies found that lasers were most effective with high rates of patient satisfaction.

Potential Treatments for TSW Identified in NIH Study

A pilot study revealed that mitochondrial complex I-blocking drugs, like metformin and berberine, improved TSW symptoms in most participants.

Thermus Thermophilus Fermentation Extract Can Treat Androgenic Alopecia

According to a clinical trial and in vitro study, TTFE can promote scalp health and hair growth by 96.88% while reducing inflammation.

Advancing Hidradenitis Suppurativa Care - Early Diagnosis, Biologic Therapies, and Multidisciplinary Approaches: Part 1

In part 1 of this Frontline Forum supplement, experts discuss the burden of HS, reducing diagnostic delays, and more.

This review of the latest dermatologic studies includes insights into supporting laser tattoo removal for adults impacted by the justice-system, a case of blastic plasmacytoid dendritic cell neoplasm, and more.

Addressing the Challenges of Pigmentary Disorders in Women Across the Fitzpatrick Skin Spectrum

Valerie Harvey, MD, MPH, FAAD, discusses pigmentary disorders like melasma and hyperpigmentation, highlighting their disproportionate impact on women, particularly those with skin of color.

Multidisciplinary Approaches to Advanced BCC and CSCC

The expert discussion focused on patient management strategies, treatment modalities, and the role of multidisciplinary collaboration.

Patients and Providers Seek More Effective, Time-Saving Treatments for Seborrheic Dermatitis

According to a survey, both patients and clinicians are unsatisfied with the current therapeutic landscape and are looking for options that better fulfill patient needs.

Post Hoc Analysis Highlights Zasocitinib’s Efficacy Across Patient Groups

The investigational drug, designed using AI technology, optimizes pharmacologic characteristics for psoriasis treatment.

Cryo-EM has elucidated the molecular mechanisms behind clindamycin resistance in Cutibacterium acnes, identifying mutations that impact antibiotic binding. Incyte's phase 3 trials of povorcitinib for hidradenitis suppurativa showed significant efficacy and safety. Social media's influence on beauty standards is causing distorted expectations. Dermatologists are urged to engage in climate advocacy and sustainable practices. Ialuxid Gel effectively treats mild to moderate acne with a 56% lesion reduction. AAD late breakers provide key insights into dermatology research, and women are celebrated for their contributions to the field.

In case you missed it, this week we had news about positive results from Incyte’s phase 3 STOP-HS trials, multidisciplinary approaches to advanced BCC and CSCC, pediatric ocular adverse effects associated with dupilumab, and more.

Sydney Givens, PA-C

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