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Patient Discussion on Treatment Satisfaction with Upadacitinib for Atopic Dermatitis


Jennifer Holman, MD, FAAD, and her patient, Audrey Dean, discuss how treatment with upadacitinib for atopic dermatitis has improved her quality of life.


Jennifer Holman, MD, FAAD: The therapy that you’re on right now, how satisfied are you? You’re…at 15 mg and have been there for 7 months now?

Audrey Dean: Yes, ma’am.

Jennifer Holman, MD, FAAD: And how satisfied are you with your current therapy?

Audrey Dean: Honestly, I’m extremely satisfied. I haven’t had a big flare-up of anything for several months. Skin’s been really clear. Scalp’s been clear. So right now it’s working for me.

Jennifer Holman, MD, FAAD: That’s a good thing…. Since you’ve been on the systemic therapy, when was the last time itch has really impacted your life day in, day out, or you’ve had to use your topical therapies?

Audrey Dean:It’s been several months. I haven’t really had to use anything.

Jennifer Holman, MD, FAAD:That’s what I want to hear. That’s a good thing. When we started, we stopped your previous therapy and started this current therapy at 15 mg a day, and we got your blood work. I gave you a bottle of samples to start. How quickly did you start to see improvement, both in your itch and your skin?

Audrey Dean:Well, I remember when I started. I think within a couple of weeks, within a month or so, I remember it was last September when I started the laser therapy. And I think I had started my current treatment around that time. [By] early October, I started noticing [that my] skin was a lot more clear. Hair was growing back. So it was [about] 3 or 4 weeks until I started noticing results.

Jennifer Holman, MD, FAAD:That’s great. And would you say that treating your atopic dermatitis with our current therapies changed your quality of life?

Audrey Dean:I think so, definitely. Less itchy. Skin’s clear. You know, I go throughout my day and I really don’t think about it unless I have someone ask me, “Hey, have you been doing with your skin stuff?” I don’t really think about it.

Jennifer Holman, MD, FAAD:Have your coworkers or your family or friends, have they noticed a difference?

Audrey Dean:Definitely. When my hair started growing back and everything, I didn’t have to wear the scrub cap at work anymore. People were like, “Oh my gosh, you look so great. Everything’s looking good.” So that was definitely great.

Jennifer Holman, MD, FAAD:….That’s a great thing.

Transcript was AI-generated and edited for clarity.

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