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New Orleans - The cosmetically engaged dermatologist has to pay attention to trends in botulinum use, according to Jean Carruthers, M.D. Dr. Carruthers and her husband, Alistair, introduced the neurotoxin for treatment of frown lines at the 1991 meeting of the American Society of Dermatologic Surgeons. The society embraced the born-again toxin and now, peering into 2004, predicts that it will prick through new frontiers. These include: enhancing upper lip fullness, treating enlarged masseter muscles, contouring the mandible area of the lower face, and eliminating multiple benign cystic lesions of the face.