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Antihistamines effective in alopecia areata study


A recent study published in the Journal of the American Academy of Dermatology found positive results when using antihistamines, along with topical corticosteroids and superficial cryotherapy, as a combination treatment for alopecia areata.

A recent study published in the Journal of the American Academy of Dermatology (JAAD) evaluated the efficacy of a combination consisting of antihistamines, topical corticosteroids (TCS) and superficial cryotherapy (SC) for the treatment of alopecia areata.

From February 2012 to November 2018, 148 patients were given a combination of TCs and SC, and 24 of those patients were also given an adjuvant antihistamine treatment of fexofenadine (180 mg/day adult, 30 mg/day children) or ebastine (10 mg/day adult).1

MORE: Antihistamines for Alopecia Areata?

The study found after seven months of treatment, 100% of antihistamine patients achieved major hair regrowth compared to 79.3% of patients who were only treated with TCs and SC. Also, the study’s authors report no adverse effects resulting from treatment.2

More information and full results of the study can be found at AestheticAuthority.com.


1. Hobbins, K. (2020, September 28). Antihistamines for Alopecia Areata? Retrieved September 29, 2020, from https://www.aestheticauthority.com/view/antihistamines-for-alopecia-areata

2. Lee YB, Lee WS. Efficacy of antihistamines in combination with topical corticosteroid and superficial cryotherapy for treatment of alopecia areata: A retrospective cohort study. J Am Acad Dermatol. 2020; epub ahead of print.

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