Psoriasis Gene to Clinic

Diet and lifestyle factors may trigger psoriasis
December 06, 2017

Environmental and lifestyle factors, such as certain foods and infections, may trigger onset of psoriasis and account for approximately 30% of the risk of the condition in people with a genetic preposition, research presented in London shows.

Impaired taste and smell may explain poor nutrition in psoriasis patients
December 06, 2017

Psoriasis has long been linked with poor nutrition, high body mass index and metabolic disorders. New research suggests a reduced sense of taste and smell, caused by inflammation, may explain why.

Genetic variation may explain why biologics help some patients, but fail others
December 06, 2017

Psoriasis patients carrying a specific gene experience a significantly better early response to ustekinumab, but are less likely to achieve high rates of response to anti-TNFs.

Cardiovascular disease in psoriasis may be due to a cardiosplenic axis
December 06, 2017

The spleen may have a role in driving the higher rate of cardiovascular disease seen in psoriasis patients through a spleen–atherosclerotic axis, suggests research presented at a meeting in London.

Restarting TNFi treatment after a break proves beneficial in psoriasis
December 04, 2017

Switching from adalimumab to etanercept or vice versa after interruption can improve treatment response, data presented in London suggests.

Promising results for risankizumab continue in phase 3 trials
December 04, 2017

Phase three trials of the selective IL-23 blocker risankizumab are replicating the promising results achieved by phase two trials for psoriasis, researchers report in London.

Hard-to-treat psoriasis cases respond to secukinumab
December 04, 2017

Secukinumab has been shown to be effective for the treatment of moderate-to-severe plaque psoriasis in hard-to-treat patients who failed anti-TNFa treatment, researchers report in London.

Caffeine can reduce inflammation in patients with eczema and psoriasis
December 01, 2017

Adding caffeine to topical skin treatments would be a simple way to reduce inflammation in patients with atopic dermatitis and psoriasis, suggests a review presented at the Psoriasis: From Gene to Clinic International Congress, which took place in London this week.

Psoriasis Gene to Clinic Congress Highlights
November 28, 2017

Experts from around the world will gather in London at the Psoriasis from Gene to Clinic Congress to present and discuss the most current developments in the understanding of psoriasis and the evidence that will steer future clinical decision making. Watch here for highlights.

Psoriasis patients have a heightened risk of malignant lymphoma
November 28, 2017

Patients with psoriasis are more likely than the general population to receive a diagnosis of malignant lymphoma. Why? Cutaneous T-cell lymphoma is misdiagnosed as psoriasis and can also be mistaken for atopic dermatitis due to similarities in the skin manifestation.