New Orleans - For J. Ramsey Mellette, M.D., avoiding pincushioning of nasal flaps taken from the nasolabial fold is difficult. "A certain degree of pincushioning in a flap that is taken from the cheek and put onto the nose is inherent in the flap because it's cheek-on-nose," said Dr. Mellette, professor of dermatology and dermatologic surgery, University of Colorado at Denver's health sciences center, department of dermatology.
LEO Pharma has closed its acquisition of dersimelagon from Tanabe Pharma after the FDA accepted the drug's NDA for filing and granted Priority Review, with a PDUFA date expected by the end of February 2027.
Sol-Gel Technologies has completed patient follow-up in its pivotal phase 3 trial of SGT-610 (patidegib gel, 2%) for Gorlin syndrome, with top-line results expected in late November 2026.
Longer treatment duration was independently associated with VASI improvement, while publicly insured patients experienced higher topical JAK inhibitor denial rates.
Though convenient, SPF-infused cosmetics rarely deliver their labeled protection level in real-world use, underscoring the continued need for a dedicated broad-spectrum sunscreen as the foundation of any routine.