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National report - Since no laser or light source meets every patient's needs, experts say it's crucial to choose technologies that will provide the maximum utility in a given practice setting.

Sewickley, Pa. - Chemical peels can be used safely and effectively for a broad range of indications and in patients of all skin types, but achieving success depends on proper skin preparation and matching the peel depth to the indication, says Suzan Obagi, M.D., director of the UPMC Cosmetic Surgery & Skin Health Center, Sewickley, Pa., and assistant professor of dermatology, University of Pittsburgh, Pittsburgh.

Portland, Ore. - A recent study confirms that the numbers of follicular melanocytes are significantly decreased in patients suffering from alopecia areata.This new insight into the often severe and psychologically burdensome disease serves as a beacon of hope for patients, as researchers begin to home in on a more precise etiology that may open the door for more targeted treatments. Past research has implicated follicular melanocytes to be the target structure in at least a proportion of patients suffering from alopecia areata.

National Report - Children with allergic contact dermatitis frequently react to the same allergens as adults with this condition do, according to a recent multi-center study conducted at the University of Miami and the University of Pennsylvania that calls for increased patch testing in children, especially those with chronic dermatitis.

National report - Registration deadline is Oct. 15 for the 2010 recertification examination for dermatologists, according to the American Board of Dermatology (ABD).

Las Vegas - Weight-based dosing with extended-release (ER) minocycline tablets allows patients with acne to achieve efficacy equivalent to that of 2 mg/kg or 3 mg/kg of body weight daily with just 1 mg/kg daily, says James Q. Del Rosso, D.O., dermatology residency director, Valley Hospital Medical Center, Las Vegas.

Las Vegas - A skin barrier protection cream (Tetrix, Coria Laboratories) appears to reduce exposure to skin allergens and irritants and decrease symptoms of eczematous dermatitis, according to James Q. Del Rosso, D.O., dermatology residency director, Valley Hospital Medical Center, Las Vegas.

New York - Cosmetic patients today have a multitude of cosmeceuticals from which to choose, and each product claims to raise the bar in its effectiveness in skin rejuvenation. Many of these products do have some degree of effectiveness, and yet others may be the cause of hardship in terms of eliciting an irritant or allergic contact dermatitis in the unfortunate user. According to one expert, physicians need to scrutinize the ingredients of these cosmeceuticals and carefully pick and choose among the vast array of products for the benefit of their patients.

Edmonton, Alberta - Although several different theories exist with regard to the pathogenesis of vitiligo, an immune basis appears to be the most favored mechanism, with cytokines and other chemical mediators playing a center role in disease development and progression. As a result, immunomodulating therapies such as tacrolimus (Protopic, Astellas) are employed.

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Washington - An advertisement for Aczone (Allergan), a gel used to treat mild-to-moderate acne, "grossly overstates" the drug’s effectiveness, the Food and Drug Administration (FDA) stated in a letter released Aug. 21.

At press time, lawmakers were still inching toward meeting a Sept. 15 deadline set by the Senate Finance Committee to reach a bipartisan compromise on healthcare reform. Dermatologists from across the country were expecting to be on Capitol Hill that day to let lawmakers know face-to-face their concerns about this sweeping legislative initiative.

Dapsone has been an important antibiotic in dermatology, especially historically, in the treatment of leprosy. It has been used for both antimicrobial and anti-inflammatory purposes orally, but no topical preparation was ever available. This is because dapsone is neither water- nor oil-soluble, presenting a formulation challenge.