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Tomato Extract May Improve Skin Health


A recent study touts the benefits of Lycomato® oral supplement for improving fine lines and wrinkles.

A daily dose of Lycomato® supplementation was shown to improve fine lines, wrinkles, pore appearance brightness, firmness, and smoothness for up to 12 weeks after use, according to a new study published in the


Journal of Cosmetic Dermatology.1 Derived from tomatoes, Lycomato is a nutrient complex that contains standardized levels of carotenoids, including lycopene (15 mg), phytoene, and phytofluene.

The open-label study involved 50 women between the ages of 35 and 55 with Fitzpatrick skin types II, III, and IV. The participants took soft gels containing 15mg of lycopene daily for 12 weeks. Their skin status was observed via questionnaires and expert visual grading of facial markers such as wrinkles, tonality, roughness, laxity, and pore size. Skin barrier was assessed using transepidermal water loss (TEWL). Visual assessments were performed by a trained expert grader at a testing laboratory, who obtained measurements before treatment and after 4 and 12 weeks of use.

The study results after 4 and 12 weeks, respectively were:

  • An average reduction of 7.2% and 8.9% (p < 0.05) in TEWL of facial skin, indicating a significant improvement in skin barrier after 12 weeks of use. 
  • 25% and 41.4% reduction of periorbital fine lines
  • 14.8% and 26% reduction of periorbital deeper wrinkles
  • 7.9% (p < 0.05) and 13.5% (p < 0.001) improvement in skin brightness and luminosity
  • 11.14% (p < 0.05) and 18.3% (p < 0.001) improvement in skin tone

Study participants also observed improvements in the self-assessment stage, reporting improvement in all perimeters after 4 weeks, and increasing after 12 weeks. Study authors concluded that the supplement improved the visual appearance of fine lines and wrinkles, skin tonality, pores, smoothness, and firmness. Lycomato soft gels are manufactured by Lycored Ltd., Beer Sheva, Israel.


1. Tarshish E, Hermoni K. Beauty from within: Improvement of skin health and appearance with Lycomato a tomato-derived oral supplement. Journal of Cosmetic Dermatology. March 2023. doi:doi.org/10.1111/jocd.15650

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