Phase 2 data presented at EADV 2026 showed daxdilimab significantly reduced disease activity and improved response rates in treatment-refractory DLE.
|Articles|September 1, 2006
Psoriasis study provides important insight into anti-inflammatory mechanism of TNF blockade
Results from a clinical study investigating the in situ mechanism of action of etanercept (Enbrel, Amgen) in the treatment of psoriasis indicate this agent, which binds both tumor necrosis factor (TNF) and lymphotoxin, breaks the cycle of dendritic cell activation and maturation and thereby decreases T-cell activation and the production of a cascade of inflammatory mediators by multiple cell types, Alice B. Gottlieb, M.D., Ph.D., says.
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