Oral antihistamines not a cure for all cutaneous itching
New Orleans - As antipruritic drugs, newer second-generation oral antihistamines, including loratadine (Claritin), cetirizine (Zyrtec), fexofenadine (Allegra), and desloratadine (Clarinex), offer several advantages compared with their predecessors. However, clinicians should be aware that these newer compounds are neither all alike nor routinely effective for controlling all types of cutaneous itch, Michael D. Tharp, M.D., said at the annual meeting of the American Academy of Dermatology.
The FDA approval, based on 36-week data from the phase 3 BRAVE-AA-PEDS trial, extends baricitinib access to patients as young as 12 years old with severe alopecia areata.
The FDA approved therapies for melanoma, dermatomyositis, superficial basal cell carcinoma, and adolescent alopecia areata, while TYK2 inhibitors and rare disease filings advanced toward 2027 decisions.