Long-term tretinoin use improves cellular atypia

Los Angeles - Dermatologists concerned that long-term topical tretinoin use might worsen epidermal cellular atypia can rest assured it does not, according to a study presented at the annual meeting of the Society for Investigational Dermatology. In fact, the treatment used commonly to rid patients of the fine lines and mottled discoloration of sun damage improves epidermal cellular atypia.