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Gene expression profile (GEP) testing outcomes have positively impacted the management decision-making process for cutaneous squamous cell carcinoma (cSCC), according to a recent study.
![atopic dermatitis on arms](https://www.dermatologytimes.com/sites/default/files/styles/trc_article_348x228/public/Atopic%20Dermatitits%20%28%C2%A9TYLimShutterstock.com%29_5.jpg?itok=XiR4u3e- "<p>“Topical botanicals could be used as an adjunctive therapy to help reach and maintain disease clearance," Leon H. Kircik, M.D. says. <small>(©TYLim/Shutterstock.com)</small></p>")
A novel cocktail of topically applied botanicals has recently proven useful in the treatment and management of mild-to-moderate atopic dermatitis in children, offering hope for this patient population.
Newer treatment approaches may soon become mainstream in the treatment and management of keloids, one expert says.
![Squamous cell carcinoma](https://www.dermatologytimes.com/sites/default/files/styles/trc_article_348x228/public/SCC_Kateryna_Kon_AdobeStock_216315059_1.jpeg?itok=z5JuQGjg "<p>“Our study demonstrates that vitamin A has a protective role against the development of SCC," says Eunyoung Cho, Sc.D.</p>")
Fruits and vegetables rich in vitamin A appear to play a significant role in helping to decrease the incidental risk of developing squamous cell carcinoma, according to a recent study.
One expert believes that clinicians may want to seek a second pathologic opinion for particularly difficult-to-diagnose melanocytic lesions before solely relying on the results of existing molecular assays.
![malignant melanoma](https://www.dermatologytimes.com/sites/default/files/styles/trc_article_348x228/public/Malignant_Melanoma_AdobeStock_lavizzara_241043808_4.jpeg?itok=BuTbuasC "<p>“The nanoparticles ... stimulated the immune system of the mice, and the immune cells learned to identify and attack cells containing the two peptides, that is, the melanoma cells," says Prof. Ronit Satchi-Fainaro.</p>")
A novel nanovaccine has demonstrated efficacy in preventing the development of melanoma in mouse models, according to a recent study.
Malignant melanoma can mimic many melanocytic lesions and vice versa, making it a difficult diagnosis. As such, accurate diagnosis should be a collaborative effort between clinician and dermatopathologist, says this expert.
There are many different aspects to the treatment and management of primary melanoma, but clinicians differ on their perceptions of the ideal treatment approach.
A recent study in experimental mice showed that interleukin-4 and interleukin-13 act as acute pruritogens, supporting the benefit of targeting these cytokines in the therapeutic planning of the patients with pruritus.
Patients with rosacea appear to have a significant increase in the risk of breast cancer when compared to those without this skin condition, according to a new study.
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