At the Johns Hopkins Cutaneous Translational Research Program (CTReP), integrating academic and clinical resources helps illuminate concepts and mechanisms that may help patients with dermatologic concerns ranging from sun damage to skin regeneration.
The program began around 10 years ago to provide an infrastructure for dermatology department research, says CTReP co-directors Anna L. Chien, M.D., and Noori Kim, M.D. Housing the CTReP within the department of dermatology’s clinic
provides easy access to laboratory and investigative resources to answer questions about diagnoses, diseases or treatments that arise during clinical care.
“We’re taking those questions right to our research unit, by designing a study, conducting the work and ultimately translating the data to better patient care,” Dr. Chien says. Faculty interests include acne, rosacea, eczema, skin cancer, photobiology and ethnic skin. “It’s a mix of different projects that goes through the unit. It really starts from the questions being developed in clinic,” Dr. Chien says.
The relative ease of skin biopsies moreover allows laboratory colleagues to check for various biomarkers, proteins or pathways, seeking correlations with what physicians are seeing clinically.
A current project involves visible light.
Dr. Chien reports no relevant fi nancial interests. The CTReP has received grants from Galderma, Johnson & Johnson, L’Oreal, Kyocera, Lutronic, Mela Sciences, Pfizer, SkinMedica, Unilever and Walgreens Boots Alliance.
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2. Sheu M. Biomarkers activated with fractionated laser. Photomedicine Society Annual Meeting. February 28, 2019. Washington, D.C.
3. OkoyeGA,Rainer BM,Leung SG, et al. Improvingacnekeloidalis nuchae with targeted ultraviolet B treatment: a prospective, randomized, split-scalp comparison study. Br J Dermatol.2014;171(5):1156-63.