Many physicians are already using platelet-rich plasma (PRP) in practice to enhance results from skin rejuvenating and hair replacement procedures. Now new scientific developments suggest that doctor's also could be using enriched platelet cells derived from the patient’s whole blood to make a personalized skincare product, according to dermatologist Zoe Diana Draelos, M.D., who practices in High Point, N.C., and founded Dermatology Consulting Services, a company that works with firms to develop formulations and conduct product testing.
Dr. Draelos says the approach is so cutting edge that her lab is testing a base serum that has been developed to maintain the viability of platelet cells.
The product base serum was introduced to dermatologists and skincare professionals at The Aesthetic Show in Las Vegas in July. Dr. Draelos, whose team oversaw the clinical study, says Aesthetics Biomedical is one company focused on the science of PRP and facial rejuvenation.
“There’s much research going on involving PRP. The reason it’s so popular is that platelet-rich plasma contains key growth factors which reside in the platelet granules,” she says.
PRP can be harvested from the blood and the enriched platelets returned to the individual through various mechanisms. It can be injected, used topically or now, as directed and provided by a physician, used in combination with the base to be applied topically at home, according to Dr. Draelos.
To prepare the topical PRP, the dermatologist draws 50 mL of blood from a patient in the office, adding an anticoagulant into the blood to avoid clotting. The doctor centrifuges the blood to extract both PRP and platelet poor plasma (PPP). Using the centrifuge that produced the study results is important to ensure a reliable, reproducible yield of platelets in the PRP, Dr. Draelos says.