Based on the meta-analysis and Hesseler et al., meta-analysis lead author Yu-Chen Huang, M.D., says she believes adjunctive PRP is a good choice for acne scarring, although the ideal PRP regimen and combination needs further clarification. Dermatologists in Asia generally believe that PRP promotes cell differentiation, proliferation and regenerationand enhances wound recovery, adds Dr. Huang. She is assistant professor of dermatology at Taipei Medical University, Taipei, Taiwan.
Dr. Hesseler says that because people have begun noticing what PRP can do for acne scars, he foresees further research with other techniques such as subcision. Dermatologists use many of these same procedures for hypertrophic scars, he says, and these procedures also may show augmented benefits with PRP.
“Although most of literature has looked at atrophic scars,” adds Dr. Hesseler, “it would be interesting to see additional research focused on other types of acne scars, as well as other types of scars altogether.”
He also believes there is still value in combining PRP with microneedling or other minimally invasive procedures for acne scarring.
“This still has to be investigated further,” Dr. Hesseler says.
Drs. Hesseler, Shyam and Huang report no relevant financial interests.
Dr. Tanghetti is a consultant for Cynosure, DEKA, Quanta, Cartessa and Aesthetics Biomedical but owns no stock in these companies.
1. Hsieh TS, Chiu WK, Yang TF, Wang HJ, Chen C. A meta-analysis of the evidence for assisted therapy with platelet-rich plasma for atrophic acne scars. Aesthetic Plast Surg. 2019 Sep 10. doi: 10.1007/s00266-019-01471-w. [Epub ahead of print]
2. Hesseler MJ, Shyam N. Platelet-richplasma and its utility in the treatment of acne scars: a systematic review. J Am Acad Dermatol.2019;80:1730-1745.
3. HuangIH, Huang YC. Comment on “Platelet-rich plasmaand its utility in the treatment of acne scars: a systematic review.” J Am Acad Dermatol. 2019 Sep 19. pii: S0190-9622(19)32761-6. doi: 10.1016/j.jaad.2019.09.024. [Epub ahead of print]