“Platelets are the first cells that show up in our wound-healing cascade. So, what we’re really doing is harnessing the body’s own wound-healing machinery and kickstarting that process with PRP,” he explains.
However, Emil Tanghetti, M.D., questions the longevity of that kickstart. He is director of the Center for Dermatology and Laser Surgery in Sacramento, Calif.
“Think of the pathophysiology. You’re putting a platelet-derived growth factor on the skin after performing a procedure,” he says. However, he says, it’s unclear if PRP works without some sort of access channels, or how long growth factors last once applied.
“The laser seems to work a little better — that’s the suggestion from the data. The problem is, most of my patients don’t want aggressive fractional ablative laser treatments,” Dr. Tanghetti says. “There’s too much downtime.”
Instead, he typically uses fractional radiofrequency (RF) microneedling for acne scars, followed by a secondary therapy to enhance effcacy with relatively minimal downtime.
Drs. Hesseler, Shyam and Huang report no relevant financial interests.
Dr. Tanghetti is a consultant for Cynosure, DEKA, Quanta, Cartessa and Aesthetics Biomedical but owns no stock in these companies.
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