Beyond the skin
There is also increasing evidence that rosacea is not only a skin disease but a systemic one as well. Patients with rosacea are at an increased risk of coronary artery disease and other forms of vascular disease, perhaps even stroke, much like psoriasis patients.
According to Dr. Baldwin, numerous studies1-2 suggest that the tetracycline class of antibiotic specifically is associated with a reduction in coronary artery disease, with one study3 finding that first-time heart attacks are most likely to occur in patients receiving tetracycline.
“It is possible that if you take the tetracycline class of antibiotics for rosacea, maybe you are not only improving the symptoms of rosacea, but you are also doing yourself a service in terms of your cardiovascular health. There is evidence that doxycycline 20 mg BID is able to reduce C-reactive protein, a marker for coronary artery disease,” Dr. Baldwin says.