The intensity and duration of the inflammatory reaction in acne causes dermal damage and alteration of the sebaceous gland structure leading to atrophic scar formation, but not all patients are affected equally.
Current and Emerging Treatments for Acne
Treatment may offer an alternative to topical retinoid treatments for acne scarring.
As both severe acne and transgenderism are independently associated with higher rates of depression and suicide, it may be advisable that transgender adolescents are monitored for acne once testosterone treatment has begun. Given the potential risks — some 41% of transgender adults have at some point attempted suicide — acne should be treated even if only mild, says Dr. Lucía Campos-Munoz.
Patient nonadherence to costly acne medications may be overcome by physicians telling patients upfront that preferred medications might be expensive.
Researchers writing in JAMA Dermatology say that the evidence for light therapies as effective acne treatments remains weak and inconclusive, but one may be worth noting.
Doctors writing in the Journal of Cosmetic Dermatology find blunt cannula subcision (BCS) more effective than Nokor needle subcision (NNS) for acne scarring.
Despite recommendations to limit the use of oral antibiotics, dermatologists continue to prescribe them in high numbers, according to results of a large, retrospective analysis of U.S. prescribing trends from 2004 to 2013.
Dermatologist evaluations of patient acne photos submitted via smartphone compare favorably to in-person evaluations, a JAMA Dermatology study shows.
The cost of doxycycline hyclate prescriptions increased 1,854% between 2011 and 2013 in a retrospective analysis of commercial claims data, and there was no association between market concentration and price of the oral antibiotic. Clinician or pharmacy level interventions to choose less costly oral tetracycline-class antibiotics could result in substantial cost savings.
Pooled meta-analysis does not support association between isotretinoin treatment for acne and worsening of depression.